Scandi is built on ingredients that have been clinically tested, published in peer-reviewed journals, and used in real oral care products for decades. Every active ingredient targets a specific mechanism — and we link the studies so you can verify the science yourself.
Nano-Hydroxyapatite (nHAp)
A biocompatible calcium phosphate that mirrors natural tooth enamel. Clinically shown to remineralize early enamel lesions, reduce hypersensitivity, and support whitening — without harsh abrasives or peroxides.
Porciani et al. (2014)Double-blind study showing calcium hydroxyapatite chewing gum significantly reduces dentin hypersensitivity after 1–2 weeks.PubMed →
Limeback et al. (2023)Systematic review confirming hydroxyapatite outperforms fluoride for dentin hypersensitivity control.PMC Full Text →
Pushpalatha et al. (2023)Comprehensive review of nanohydroxyapatite for enamel and dentin remineralization.PMC Full Text →
Sodium Phytate & Sodium Hexametaphosphate
Chelating agents that bind to calcium ions in stains, preventing new discoloration and loosening existing chromogens. Non-abrasive, non-peroxide whitening that preserves enamel integrity.
Gerlach et al. (2002)RCT demonstrating sodium hexametaphosphate dentifrices for effective extrinsic stain removal.PubMed →
Gerlach et al. (2002, related)Additional data on stain removal efficacy.ResearchGate →
Cui et al. (2025)RCT on sodium phytate-containing whitening toothpaste showing notable whitening effects.PubMed →
Zinc Citrate & Zinc Gluconate
Zinc ions inhibit volatile sulfur compounds (VSCs) — the primary cause of bad breath — and reduce odor-producing bacteria for sustained freshness well beyond chewing.
Chen et al. (2009)Clinical evidence on zinc citrate dentifrice reducing odor-producing microorganisms.IADR →
Josic et al. (2024)Double-blind RCT on zinc-citrate + hydroxyapatite toothpaste showing superior antibacterial efficacy.PubMed →
Suzuki et al. (2018)Mechanistic study on zinc ions binding to hydrogen sulfide and inhibiting malodor.PMC Full Text →
Xylitol & Erythritol
Non-fermentable sugar alcohols that cannot be metabolized by oral bacteria into enamel-damaging acids. Long-term studies show reduced S. mutans levels, less plaque, and lower caries incidence.
Janakiram et al. (2017)Systematic review & meta-analysis supporting xylitol for caries prevention.PMC Full Text →
Pienihäkkinen et al. (2024)Systematic review confirming caries-reducing effects of xylitol chewing gum.PMC →
Honkala et al. (2014)3-year RCT showing erythritol and xylitol effectively prevent caries, with erythritol performing strongly.PubMed →
